DescriptionA standard procedure in many areas of bioinformatics is to use a multiple sequence alignment (MSA) as the basis for various types of homology-based inference. Applications include 3D structure modelling, protein functional annotation, prediction of molecular interactions, etc. These applications, however sophisticated, are generally highly sensitive to the alignment used, and neglecting non-homologous or uncertainty in the alignment can lead to significant bias in the subsequent inferences.
Associated topics.  

How to use:Expand/collapse node by clicking on them.